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The more we are exposed to the less we shun.

Holoprosencephaly (HPE) refers to a range of problems involving the malformation of the brain and upper face along the mid line. This is extremely rare in live births (~1 in 15,000), but is more commonly detected in early pregnancies (1 in 250); however almost all affected fetuses are miscarried. The cause of these deformities is thought to be due to mutations in the SHH gene

Chinese baby has a birth defect that makes him permanently look like he has a mask on.

A baby born without pupils. Unfortunately, there is no way to fix this and the baby is blind.

Yes, I looked this up. Absolutely shocking. "Lina Medina is the youngest confirmed mother in medical history, giving birth at the age of five years, seven months and 17 days. From a remote village in Peru, in 1939 Medina was brought to a hospital by her parents due to increasing abdominal size. She was originally thought to have had a tumor, but her doctors determined she was in her seventh month of pregnancy."

"Edward Mordrake was a 19th century English nobleman who had an extra face on the back of his head. According to the story, the extra face could neither eat nor speak, but it could laugh and cry. Edward begged doctors to have his ‘devil twin’ removed, because, supposedly, it whispered horrible things to him at night, but no doctor would attempt it. He committed suicide at the age of 23 by poisoning himself because he could no longer stand having to live with the face on the back of his head."

Ectrodactyly, sometimes referred to as the “lobster-claw syndrome” involves the deficiency or absence of one or more central digits of the hand or foot and is also known as split hand/split foot malformation (genetics)

ca. 1875, [portrait of a father and his daughter, suffering from hydrocephalus] via A Morning’s Work: Medical Photographs from the Burns Archive, Stanley B. Burns

Born with a beautiful face and giant feet, Fanny Mills came with a dowry of five thousand cash and a “well stocked farm” in Ohio from her desperate father, to any single men willing to take her as bride.

Rhinoplasty. Loss of nose due to an injury, and replacement by a finger in 1880. Surgery by Dr. E. Hart, photo by OG Mason, both of Bellevue Hospital, NY.