Belle Gunness, a Norwegian-American serial killer, killed her children, her many husbands, and various other people (more than 40) for insurance payouts and cash. Belle faked her own death and eluded capture and trial. ca 1908
This is from a great Blog, Murder by Gaslight. Dr Thomas Neill Cream was one of the few men from Chicago suspected of being Jack the Ripper. He was a serial killer, abortionist and poisoner. He looked just like Snidely Whiplash, so you know he's a villain. Hell, just look at the top hat, cool moustache and monocle, pure evil!!