A slow, chronic starvation of the brain as we age may be a main triggers of a biochemical process that causes some forms of Alzheimer's disease. A newly released study from Northwestern University's Feinberg School of Medicine has found when the brain doesn't get enough sugar glucose -- as might occur when cardiovascular disease restricts blood flow in arteries to the brain -- a process is launched that ultimately produces the sticky clumps of protein that appear to be a cause of Alzheimer's.
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Changes in the Brain in Alzheimer's Disease - Alzheimer’s disease is an irreversible, progressive brain disease that slowly destroys memory and thinking skills, and eventually even the ability to carry out the simplest tasks. In most people with Alzheimer’s, symptoms first appear after age 60. Estimates vary, but experts suggest that as many as 5.1 million Americans may have Alzheimer’s disease.
Molecular Trigger for Alzheimer's Disease Identified: Researchers at Cambridge’s Department of Chemistry have pinpointed a catalytic trigger for the onset of Alzheimer’s disease – when the fundamental structure of a protein changes to cause a chain reaction that leads to the death of neurons in the brain. For the first time, they have been able to map in detail the pathway that generates “aberrant” forms of proteins which are at the root of neurodegenerative conditions such as Alzheimer’s.