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David Bowie has a condition called anisocoria, which is the medical term for unequal pupils. At 14, he got punched in the eye by his schoolfriend, which caused his pupil to remain permanently open. Some people think his irises are two different colors, but you can see here that they are not.

Crohn's disease is a type of inflammatory bowel disease that can be incredibly challenging. In Crohn's disease, a rogue immune system attacks the digestive tract, causing inflammation and tissue damage. Symptoms include abdominal cramps, diarrhea, fever, & fatigue. Celebrities include Cynthia McFadden, Shannen Doherty, Dwight D. Eisenhower, and many others.

Living with multiple sclerosis can be even more challenging when you're a celebrity. Learn how the stars cope with this debilitating disease.

11 Female Celebrities with IBD and/or IBS Glad I'm not alone. It's not just a UGLY disease.

A look at famous people and celebrities with thyroid conditions including hypothyroidism, hyperthyroidism, Hashimoto's disease, Graves' disease, and nodules. Oprah Winfrey, Rod Stewart, Missy Elliot, Roger Ebert, Sofia Vergara, Tipper Gore, Kelly Osbourne, Kim Cattrall, Linda Ronstadt, Jillian Michaels.

Jack Osbourne didn't hide his multiple sclerosis while working towards the finale of "Dancing with the Stars." He's raised awareness of the debilitating disease. Learn about other celebrities raising awareness about important conditions.

Celebrities with Crohns disease battle Crohns symptoms in the public eye. Find out which celebrities are increasing awareness of Crohns.

The lowdown on celiac disease, gluten sensitivity and celebrity wheat-bashing: In conversation with Dr Alessio Fasano

10 Celebrities with Lyme, In the Lyme Light

Celebrate National Walking Day With Seniors

Frank Fritz, one of the stars of the History Channel's reality series American Pickers, is an antiques treasure hunter who has battled Crohn's for more than a quarter century. "Crohn's is like a duck," he told Crohn's Advocate magazine. "Ducks look calm, floating quietly on the surface of the water, but underneath they are paddling like crazy. It's the same for people with Crohn's—on the outside you can't really tell, but I'm working really hard to stay in control as much as I can."