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Evol Creative
Evol Creative • 1 year ago

Methoxetamine (MXE) or 3-MeO-2-Oxo-PCE is a chemical of the arylcyclohexylamine class which has been sold as a designer drug.[1] It is a derivative of ketamine that also contains structural features of eticyclidine and 3-MeO-PCP. Methoxetamine is thought to behave as a NMDA receptor antagonist and dopamine reuptake inhibitor, though it has not been formally profiled pharmacologically.

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Phencyclidine (a complex clip of the chemical name 1-(1-phenylcyclohexyl)piperidine), (PCP) and known colloquially as angel dust or wet, is a recreational dissociative drug. Formerly used as an anesthetic agent, PCP exhibits both hallucinogenic and neurotoxic effects. PCP is an NMDA receptor antagonist.PCP is an NMDA receptor antagonist. PCP, like ketamine, also acts as a D2 receptor partial agonist. D2 receptor antagonists (such as haloperidol) can be used in the treatment of PCP psychosis.

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Atropine is a competitive antagonist for the muscarinic acetylcholine receptor types M1, M2, M3, M4 and M5. It is classified as an anticholinergic drug (parasympatholytic). Enters CNS. Physostigmine is the CNS antidote for atropine.

Ipratropium bromide (INN, trade names Atrovent, Apovent, Ipraxa and Aerovent) is an anticholinergic drug used for the treatment of chronic obstructive pulmonary disease and acute asthma. It blocks the muscarinic acetylcholine receptors in the smooth muscles of the bronchi in the lungs, opening the bronchi.

Naloxone is an opioid inverse agonist drug developed by Sankyo in the 1960s.Naloxone is a drug used to counter the effects of opiate overdose, for example heroin or morphine overdose. It is marketed under various trademarks including Narcan, Nalone, and Narcanti.

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Indomethacin (lndocin) is a non-steroidal anti-inflammatory drug (NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling.

Serotonin syndrome (serotonin toxicity) is a life-threatening consequence of excess serotonergic activity at CNS and peripheral serotonin receptors due to drugs. Treatment consists of discontinuing offending medications & administering a serotonin antagonist. An important adjunct treatment includes controlling agitation with benzodiazepine sedation. Libby Z. (Phenelzine & Demerol) died from serotonin syndrome & consequently changed graduate medical education in NYS. Serotonin pictured.

Melatonin also known chemically as N-acetyl-5-methoxytryptamine,[1] is a naturally occurring compound found in animals, plants, and microbes.[2][3] In animals, circulating levels of the hormone melatonin vary in a daily cycle