Old Spanish Fort, also known as Old French Fort and LaPointe-Krebs House, was constructed circa 1721 on the shore of Lake Catahoula (Krebs Lake) near what is now Pascagoula, Mississippi, by French Canadian Joseph Simon de la Pointe. Old Spanish Fort is often described as the oldest building in the Mississippi River Valley. The structure was added to the National Register of Historic Places in 1971. Old Spanish Fort is owned by the city of Pascagoula and serves as a museum.
Lynn Meadows Discovery Center, Gulfport MS, one of the top 50 Childrens Museums in the country
Ohr-O'Keefe Museum of Art in Biloxi was designed by Frank Gehry, architect. Some of the locals think the "pods" look like tin cans.