I'm also just gonna point out that on "Shut up, Dr. Phil" (where the married witch couple was trying to kill each other) Don (the husband) had a photo of (what I'm asuming to be) Trump Towers and it was signed by "D. Trump" with some kind of message and Dean called him "the Trumpster". I was rewatching that one and found it hilarious
Imagine the reaction of Sam and Dean... "Son of a bitch!!! Sam, get all the borax you can find! I'm sharpening the blades!" Sam, while rummaging through the cleaning supplies: "We need to find the source, and the processing plant. I'll look into any weird activity on that. We got this Dean. We got this."