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Alpha Adrenergic Agonist

AUTONOMIC DRUGS; PART 3; Alpha & Beta Adrenergic Agonists by Professor Fink


Adrenergic Receptor System Summary


alpha and beta blockers | Beta 1 Agonists


Multiple System Atrophy aka Shy-Drager Disease... Parkinsonism + Autonomic Dysfunction + Neurological Signs... increased falls, dizziness, orthostatic hypotension, erectile dysfunction, resting tremor, rigidity, bradykinesia... Treated with intravascular volume expansion, fludrocortisone, salt supplements, alpha adrenergic agonists, and constrictive garments


β1 (eg metoprolol is a β1 blocker) & β2 (eg albuterol is a β2 agonist) receptors work by Gs (AC -> cAMP -> PKA), while α1 (eg terazosin is an α1 blocker) work by Gq (PLC -> PIP2, IP3 -> Ca2+, DAG -> PKC. Besides the heart, β1 receptors are used for aqueous humor production.


AUTONOMIC DRUGS; PART 3; Alpha & Beta Adrenergic Agonists by Professor Fink - YouTube

Heart Failure Medication: Beta-Blockers, Alpha Activity, Beta-Blockers, Beta-1 Selective, ACE Inhibitors, ARBs, Inotropic Agents, Vasodilators, Nitrates, B-type Natriuretic Peptides, I(f) Inhibitors, ARNIs, Diuretics, Loop, Diuretics, Thiazide, Diuretics, Other, Diuretics, Potassium-Sparing, Aldosterone Antagonists, Selective, Alpha/Beta Adrenergic Agonists, Calcium Channel Blockers, Anticoagulants, Cardiovascular, Opioid Analgesics


Behavioral Genetics Influences on Child Eating and Weight Development : Parental Obesity Status Predicts Child Overweight Status: The Familial Association

Gonioscopic examination of a traumatic angle recession shows widening of the ciliary body band. Separation between the longitudinal and circular muscle of the ciliary body (commonly caused by blunt injury to the eye) Incidence of intraocular pressure elevation appears to be directly related to the extent of angle involvement (may require at least 180 or 270 degree involvement) Clinical features: Symptoms: May be asymptomatic In the acute phase following injury, early onset glaucoma may…