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Differences Between B-Cells and T-Cells. T cells and B cells are the major cellular components of the adaptive immune response. T cells are involved in cell-mediated immunity, whereas B cells are primarily responsible for humoral immunity.


T cell-dependent B cell activation, showing a TH2-cell (left), B cell (right), and several interaction molecules wikipedia


"B cells are lymphocytes that play a large role in humoral immune response (as opposed to cell-mediated immune response governed by T cells). Essential component of adaptive immune system. Precursors of plasma cells, are characterized by presence of a B-cell receptor able to bind specifically an antigen. Principal functions are to make antibodies against antigens, perform role of antigen-presenting cells (APCs), eventually develop into memory B cells after activation by antigen…


Vast numbers of cells that can attack cancer and HIV have been grown in the lab, and could potentially be used to fight disease


Multiple Myeloma. IgG 55% > IgA > light chain only > IgD > biclonal > IgE > nonsecretory 1%. IgM is considered LPL or SLL but NOT myeloma. Usually kappa, but for IgD it's lambda! People with negative SPEP probably have light chain only myeloma and 2% have non-secretory. NEOPLASTIC plasma cells = CD38, 138, restricted light chain, and CD56 which not only implies neoplastic, but also that it's more aggressive. Do NOT express B cell markers but 10-30% express myelomonocytic, some have CD10…