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Cannabidiol (CBD), one of the chemical components found in marijuana, may have fast-acting antidepressant effects, according to a study published in Neurop ...

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WAKE UP AMERICA LOOKS WHATS IMPOSTORS OF YOUR FOOD! 1. MSG (Monosodium Glutamate) This salt form of glutamate, or glutamic acid, has been known to trigger headaches for decades. Glutamate easily crosses the blood-brain barrier, stimulating cell receptors that triggers cell death. While the body naturally produces glutamate when needed to trigger cell termination, flooding the body with dietary glutamate can seriously disrupt normal cellul…

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Structural States of a Brain Receptor Revealed - NeuroscienceNews.com - Structure of the glutamate receptor, showing the part where glutamate binds outside the cell and the part that spans the cell membrane (between the dotted lines). Image Credit Subrama

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Exciting & Calming Your Brain: GABA & Glutamate in Fibromyalgia/ME/CFS

Glutamate can become what's called an "exitotoxin," meaning that it appears to excite neurons until they die, In FMS, research shows abnormally high levels of glutamate in a part of the brain called the insula or insular cortex. Researchers went looking there because that area is highly involved in pain and emotion, which are key components of the condition. In ME/CFS, some researchers hypothesize that glutamate function is low, which means the brain isn't getting enough stimulatio

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This illustration shows a synapse. When an action potential arrives at a synapse, the positive charge causes the opening of voltage gated calcium channels. Calcium pours into the synaptic button and binds to several proteins, changing their shape. The activated proteins dynamically rearrange the blue cytoskeleton to transport green vesicles filled with yellow neurotransmitters to the synaptic cleft, which is filled with red adhesion proteins. Calcium-activated SNARE proteins bind to both…

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Ketamine Cousin Rapidly Lifts Depression Without Side Effects. - Research in the field dampened until a glutamate receptor antagonist already approved for anesthesia, and known on the streets as “Special K”, ketamine, made headlines in the early 2000s. Human clinical studies demonstrated that ketamine can ward off major and bipolar depressive symptoms within 2 hours of administration and last for several days.

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