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"Immune globulin products from human plasma were first used in 1952 to treat immune deficiency. Intravenous immunoglobulin (IVIG) contains the pooled immunoglobulin G (IgG) immunoglobulins from the plasma of approximately a thousand or more blood donors. Initially, immune globulin products were administered by intramuscular injection..." Schematic representation of an immunoglobulin G mo

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Multifocal motor neuropathy: long‐term clinical and electrophysiological assessment of intravenous immunoglobulin maintenance treatment | Brain

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This links to the abstract for the case study: "Paradoxical response to intravenous immunoglobulin in a case of Parvovirus B19-associated chronic fatigue syndrome." http://www.ncbi.nlm.nih.gov/pubmed/25542471

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IVIG or Intravenous Immunoglobulin is the blood product that is administered intravenously. This blood product comes with the polyvalent, pooled, IGG antibodies

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Intravenous immunoglobulin in neurology—mode of action and clinical efficacy : Intravenous immunoglobulin (IVIg)—a preparation of polyclonal serum IgG pooled from thousands of blood donors—has been used for nearly three decades, and is proving to be an efficient anti-inflammatory and immunomodulatory treatment for a growing number of neurological diseases. Evidence from controlled clinical trials has established IVIg as a first-line therapy for Guillain–Barré syndrome, chronic inflammatory…

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Blood Journal | Effects of intravenous immunoglobulin on platelet count and antiplatelet antibody disposition in a rat model of immune throm...