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Progressive Multifocal Leukoencephalopathy Information Page: National Institute of Neurological Disorders and Stroke (NINDS)

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Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease which results from the JC virus infecting oligodendrocytes. It is considered the most common clinical manifestation of JC virus infection in the brain. Patients with PML present with various neurological symptoms. It typically spares the optic nerve and the spinal cord. Read more: http://radiopaedia.org/articles/progressive-multifocal-leukoencephalopathy

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Stephanie explains progressive multifocal leukoencephalopathy (PML) and the John Cunningham Virus (JCV) and their relationship to MS.

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from Bel Marra Health - Breaking Health News and Health Information

Multiple sclerosis, psoriasis drug ingredient linked to a lethal brain infection

Multiple #sclerosis and #psoriasis drug ingredient – dimethyl fumarate – was found to be associated with PML (progressive multifocal leukoencephalopathy), which is a lethal #brain infection. #Medication #Health @belmarra

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A case of PML (progressive multifocal leukoencephalopathy) has been reported in a person with MS being treated with Gilenya. To date, 11 PML cases in people with ‪#‎MS‬ have been reported, but all had occurred in someone previously on Tysabri. Read more: http://msology.ca/pml-case-reported-with-gilenya

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In launching this discussion, Patricia Coyle, MD,  examines the oral immunosuppressive medications that have been shown to increase a multip...In launching this discussion, Patricia Coyle, MD, examines the oral immunosuppressive medications that have been shown to increase a multiple sclerosis (MS) patient’s risk of developing progressive multifocal leukoencephalopathy (PML). -

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