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Flavonols inhibit proinflammatory mediator release, intracellular calcium ion levels and protein kinase C theta phosphorylation in human mast cells. - PubMed - NCBI

P38 Signaling: Cellular responses to many external stimuli involve the activation of several types of MAPK (Mitogen-Activated Protein Kinase) signaling pathways. MAPKs are a family of Serine/threonine kinases that comprise 3 major subgroups, namely, ERK (Extracellular signal–Regulated Kinase), p38 MAPK and JNK (c-Jun N-terminal Kinases). Despite the diversity in function and upstream signaling events, MAPKs are.... http://www.sabiosciences.com/pathway.php?sn=P38_Signaling

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Bitter melon has been analyzed by Western scientists to contain substances that stimulate AMPK (AMP-activated protein kinase).

Glutathione peroxidase mimic; peroxynitrite scavenger. Inhibits lipoxygenase, cyclooxygenase, nitric oxide synthase, protein kinase C and H+/K+-ATPase activity. Inhibits the hepatic carcinogenic effec ts of aflatoxin B1. Antioxidant and anti-inflammatory. Tocris Bioscience 5245 Feedback Form

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Asymmetric responses of the woody poplar taproot axis to bending stress

Mechanical bending stress can result in cell wall strengthening and increased wood formation across root axes together with an attendant asymmetrical accumulation of phytohormones. De Zio et al. show how different mechanical force intensities act across the compressed concave and stretched convex sides of the woody bent poplar taproot. Model summarizing the main anatomical phytohormonal and proteomical changes observed in the convex and concave sides of three bent taproot sectors (ABS BS…

Neuroprotective targets involved in mechanism of action of the multifunctional iron chelating compounds (e.g. M30, HLA20). Full explanation is discussed in the text. Abbreviations; brain derived neurotrophic factor (BDNF); erythropoietin (EPO); extracellular signal-regulated kinase (ERK); hypoxia-inducible factor (HIF); glucose transporter 1 (GLUT-1); glycogen synthase kinase 3 (GSK-3)β; PI3K, phosphatidylinositol 3-kinase protein kinase C (PKC); transferrin receptor (TfR); tyrosine…

Cell image CIL:13719 NCBI Organism: Homo sapiens Cell Types: endothelial cell Cell Lines: HeLa,cervical carcinoma Cellular Components: mitochondrion,mitochondrial outer membrane translocase complex,mitochondrial inner membrane,mitochondrial outer membrane Biological Process: protein targeting to mitochondrion,response to stress,protein phosphorylation,intracellular protein kinase cascade Molecular Function: P-P-bond-hydrolysis-driven protein transmembrane transporter activity,protein…