Receptor tyrosine kinases (RTK)s are very important signaling pathway, which not only include growth factor receptors such as EGFR(HER), VEGFR, PDGFR, FGFR, IGF-1R, Mast/stem cell growth factor receptor (c-Met) and HER2, but also other gene products which are expressed by the oncogenes such as SRC, Bcr, c-Met and Abl as well.
Access : Tyrosine kinase receptors as molecular targets in pheochromocytomas and paragangliomas : Modern Pathology
Myasthenia Gravis. Myasthenia gravis (MG) was first described by Thomas Willis in 1672. It is an acquired autoimmune disease with antibodies against the nicotinic acetylcholine receptor (AChR) at the neuromuscular junction or muscle-specific tyrosine kinase (MuSK). This leads to muscular weakness with easy 'fatiguability', which is worse on exercise and improves with rest. (read more here)
Video Abstract: The Evolving Role of Maintenance Therapy Using Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors (EGFR GKIs) in the Management of Advanced Non-Small Cell Lung Cancer