The DNA and Chromosome Aberrations Branch of the Division of Cancer Biology, NCI, plans and administers a broadly-based extramural program of grants in the area of cancer genetics and epigenetics, including regulation of gene expression, mechanisms of DNA damage/repair, genomic instability and related molecular, cytogenetic, and chromosomal effects during induction and progression to malignancy.

The DNA and Chromosome Aberrations Branch of the Division of Cancer Biology, NCI, plans and administers a broadly-based extramural program of grants in the area of cancer genetics and epigenetics, including regulation of gene expression, mechanisms of DNA damage/repair, genomic instability and related molecular, cytogenetic, and chromosomal effects during induction and progression to malignancy.

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation — ScienceDirect

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation — ScienceDirect

Nitrosation and oxidation in the regulation of gene expression

Nitrosation and oxidation in the regulation of gene expression

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals.

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals.

Deep RNA sequencing has emerged as a powerful technology for transcriptome analysis. By generating massive amount of short sequence reads from a given RNA sample, one can use RNA-Seq to define and quantify patterns of gene expression and RNA processing on a genomic scale. This project will develop methods for analysis of transcriptome complexity (gene expression, RNA processing, non-coding RNA) using RNA-Seq data, and apply these methods to study transcriptome regulation and mRNA isoform…

Deep RNA sequencing has emerged as a powerful technology for transcriptome analysis. By generating massive amount of short sequence reads from a given RNA sample, one can use RNA-Seq to define and quantify patterns of gene expression and RNA processing on a genomic scale. This project will develop methods for analysis of transcriptome complexity (gene expression, RNA processing, non-coding RNA) using RNA-Seq data, and apply these methods to study transcriptome regulation and mRNA isoform…

In this review, the authors highlight how some of the lncRNAs implicated in cancer are involved in the epigenetic control of gene expression. While very few lncRNAs have already been identified as players in determining the cancer-survival outcome in a number of different cancer types, for most of the lncRNAs associated with epigenetic regulation only their altered pattern of expression in cancer is demonstrated. Thanks to their tissue-specificity features, lncRNAs have already been…

In this review, the authors highlight how some of the lncRNAs implicated in cancer are involved in the epigenetic control of gene expression. While very few lncRNAs have already been identified as players in determining the cancer-survival outcome in a number of different cancer types, for most of the lncRNAs associated with epigenetic regulation only their altered pattern of expression in cancer is demonstrated. Thanks to their tissue-specificity features, lncRNAs have already been…

Pinterest
Search