16th-century Ottoman miniature of the Battle of Chaldiran.-In 1511, Ismail had supported an pro Shia/Safavid uprising in Anatolia, the Şahkulu Rebellion. In 1514, Selim I attacked Ismā'il's kingdom to stop the spread of Shiism into Ottoman dominions. Selim and Ismā'il had been exchanging a series of belligerent letters prior to the attack. Selim I defeated Ismā'il at the Battle of Chaldiran in 1514
Selim I was the Sultan of the Ottoman Empire from 1512 to 1520. His reign is notable for the enormous expansion of the Empire, particularly his conquest between 1516 and 1517 of the entire Mamluk Sultanate of Egypt, which included all of Sham, Hejaz, Tihamah, and Egypt itself. He was also granted the title of "Khâdim ül Haramain ish Sharifain" (Servant of the Holy Cities of Mecca and Medina) by the Sharif of Mecca in 1517.