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The human genome contains 3 billion chemical nucleotide bases (A, C, T, and G). The average gene consists of 3,000 bases, but sizes vary greatly. The largest known human gene is dystrophin at 2.4 million bases. The total number of genes is estimated at 30,000—much lower than previous estimates of 80-140,000. Almost all (99.9%) nucleotide bases are exactly the same in all people. The functions are unknown for over 50% of discovered genes.