HSP40 Resource Guide

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Heat Shock Protein 40 (HSP40) information database. A resource for all HSP40 structure, isoform, function, disease relevance, and inhibitor information.
HSP40 Resource Guide
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Cells with severely altered kDNA are able to initiate cell division.

Mitochondrial chaperones have multiple functions that are essential for proper functioning of mitochondria. In the human-pathogenic protist Trypanosoma brucei, we demonstrate a novel function of the highly conserved machinery composed of mitochondrial .

The ultrastructure of kDNA is severely altered in mtHsp70- and mtHsp40-depleted cells.

The ultrastructure of kDNA is severely altered in and cells.

DnaJA1 is recruited into the nucleus upon influenza virus infection.

is recruited into the nucleus upon influenza virus infection.

Heat-stress induces transient longitudinal growth arrest succeeded by monopolar growth.

Heat-stress induces transient longitudinal growth arrest succeeded by monopolar growth.

Genome-Wide Identification of Hsp40 Genes in Channel Catfish and Their Regulated Expression after Bacterial Infection

Genome-Wide Identification of Genes in Channel Catfish and Their Regulated Expression after Bacterial Infection

Nucleotide-Dependent Interactions within a Specialized Hsp70/Hsp40 Complex Involved in Fe–S Cluster Biogenesis

Nucleotide-Dependent Interactions within a Specialized Complex Involved in Fe–S Cluster Biogenesis

Figure 1.  Constructs of Sis1 used in plasmid-shuffling experiments.

Figure Constructs of used in plasmid-shuffling experiments.

The result of ISH in mouse testis at various developmental periods.

The result of ISH in mouse testis at various developmental periods.

Model of Hsp70:J-protein chaperone cycle

Model of chaperone cycle

Structural classification of J-proteins

Structural classification of J-proteins

Western blot of A431 lysates showing the detection of ~47 kDa Hsp47 protein using Anti-Hsp47 antibody [1C4-1A6] (SMC-203).

Antibody - Mouse monoclonal antibody to human Heat Shock Protein clone Validated for use in Western Blot and ICC/IF with human tissue.

Immunocytochemistry analysis using Mouse Anti-Hsp47 Monoclonal Antibody. Tissue: Heat Shocked HeLa Cells. Fixation: 2% Formaldehyde for 20 min at RT. Primary Antibody: Mouse Anti-Hsp47 Monoclonal Antibody (SMC-203B) at 1:100 for 12 hours at 4°C. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:200 for 120 min at RT. Counterstain: DAPI (blue) nuclear stain at 1:40000 for 120 min at RT. Localization: Endoplasmic reticulum lumen. Cytoplasm. Magnification: 100x. (A) DAPI (blue) nuclear…

Explore our range of antibodies, proteins, assay kits, and small molecules.

Immunocytochemistry analysis using Mouse Anti-Hsp47 Monoclonal Antibody. Tissue: Heat Shocked HeLa Cells. Fixation: 2% Formaldehyde for 20 min at RT. Primary Antibody: Mouse Anti-Hsp47 Monoclonal Antibody (SMC-203B) at 1:100 for 12 hours at 4°C. Secondary Antibody: APC Goat Anti-Mouse (red) at 1:200 for 120 min at RT. Counterstain: DAPI (blue) nuclear stain at 1:40000 for 120 min at RT. Localization: Endoplasmic reticulum lumen. Cytoplasm. Magnification: 20x. (A) DAPI (blue) nuclear stain…

Explore our range of antibodies, proteins, assay kits, and small molecules.

Western blot analysis of Hsp40 YDJ1 in a human cell line mix using a 1:1000 dilution of SMC-150.

Western blot analysis of in a human cell line mix using a dilution of

SMC-145,-Hsp40-HDJ1-(3B9-E6),-Human-Cell-Line-Mix.jpg (480×361)

Mouse Antibody used in Western Blot (WB) on Human Cell lysates

HSP40 Drug Discovery - Quercetin, KNK437, butyl 3-[2-(2,4-dichlorophenoxy)acetamido]benzoate

HSP40 Drug Discovery - Quercetin, KNK437, butyl 3-[2-(2,4-dichlorophenoxy)acetamido]benzoate