Nerve Fiber
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Nerve fiber

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Nerve fibers of the peripheral nervous system are myelinated, consisting of Schwann cells. Each fiber is surrounded by the endoneurium consisting of loose connective tissue. The fibers are gathered in bundles called fascicles and each fascicle is wrapped in the perineurium. The perineurium is composed of overlapping epithelium-like cells. Several fascicles also bundle together and wrapped in the epineurium which consist of dense irregular tissue and protects the nerve from stretching and…
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Nodes of Ranvier, or neurofibril nodes, are discontinuities in the myelin sheath of nerve fibers that permit depolarization of the axon. They are integral parts of nerve fibers in the CNS and PNS. They act as relay stations during saltatory conduction, enabling the impulse to jump from node to node. The nodes were named after French histologist and pathologist Louis-Antoine Ranvier who observed these myelinated peripheral nerve fibers and discovered these interruptions in the 19th…
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