The Savior told us that He has descended below ALL things and that He suffered for all things - not just your sins but also you pain and heartache and sadness and, yes, those bumps and bruises along the way. In Joy!
God says "the reason why some people have turned against you and walked away from you without reason...has nothing to do with you. It is because I have removed them from your life because they cannot go where I AM taking you next. They would only hinder you at the next level because they have already served their purpose in your life. Let them go and keep moving. Greater is coming your way...says the Lord.