The retina contains five classes of neurons: photoreceptors (purple), horizontal cells (yellow), bipolar neurons (green), amacrine cells (pink and blue), and ganglion cells (pink and blue). In this cross section of an adult mouse retina, only a subset of bipolar cells, “the ON bipolar cells” are visible by their expression of GFP (green). The pink and blue speckled striations at the bottom of the image mark the fiber layer, which contains the ganglion cell axons that will form the optic nerve
Coloured light micrograph of a 1-week old, nerve cell (neuron) cluster. This cell cluster has been grown in culture. The nerve cell bodies are still grouped together (centre) and the neurites (either axons or dendrites) that will connect the cell bodies to form a network, are beginning to develop (dark lines).
Retinal pigment epithelium precursor cells Human embryonic stem cells differentiating into precursors cells of the retina. Nuclei are in blue. Pink indicates the presence of Pax6, a protein found in retinal tissue. The retinal pigment epithelium is the tissue responsible for macular degeneration, the most common cause of blindness. This photo was taken in the lab of David Buchholz at the University of California, Santa Barbara. Learn more about CIRM-funded stem cell research: www.cirm.ca.gov