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2. 1966 Shelby Cobra 427 5,540 votes, 15 percent of the vote Although not purely American, the 427 Cobra is one of the best-known muscle cars ever made. Based on a lightweight British AC Ace roadster, the Cobra was the brainchild of automotive legend Carroll Shelby, and it was essentially created by shoehorning a mammoth Ford 427 engine under the AC's hood. The end result was a frighteningly fast roadster that was also tremendously successful on the track. Today, top examples of these…