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PPI effect- Proton pump inhibitors (PPI) block the H+K+ ATPase producing a low acid environment in the stomach. This, in turn, stimulates gastrin which has a trophic effect on parietal cells giving them a “juicy” appearance

PPI effect- Proton pump inhibitors (PPI) block the H+K+ ATPase producing a low acid environment in the stomach. This, in turn, stimulates gastrin which has a trophic effect on parietal cells giving them a “juicy” appearance

Normal body-type gastric mucosa. Autoimmune chronic atrophic gastritis is restricted to body (not antrum). Antiparietal cell antibodies and anti-IF antibodies, +/- pernicious anemia. Destroy acid-producing parietal cells, leading to achlorhydria, which in turn stimulates gastrin leading to hypergastrinemia and ulcers.

Normal body-type gastric mucosa. Autoimmune chronic atrophic gastritis is restricted to body (not antrum). Antiparietal cell antibodies and anti-IF antibodies, +/- pernicious anemia. Destroy acid-producing parietal cells, leading to achlorhydria, which in turn stimulates gastrin leading to hypergastrinemia and ulcers.

Normal fundic mucosa

Normal fundic mucosa

Hiatal hernia. Assessment: dyspepsia, regurgitation, heartburn. Implementation:  small, frequent feedings. Don't lie down for 1 hr after eating. Elevate head when sleeping. Meds: H2 receptor blockers, antacids, cytoprotective agents (like Carafate, given on empty stomach). Surgery: fundoplication.

Good way to describe hiatal hernia to patients

Mentriere's disease. Marked BODY foveolar hyperplasia with hypochlorhydria and protein-losing enteropathy/hypoproteinemia. Chronic and severe in adults. Mild atrophy of the underlying secretory mucosa.

Marked BODY foveolar hyperplasia with hypochlorhydria and protein-losing enteropathy/hypoproteinemia. Chronic and severe in adults. Mild atrophy of the underlying secretory mucosa.

This is the normal appearance of the gastric fundal mucosa, with short pits lined by pale columnar mucus cells leading into long glands which contain bright pink parietal cells that secrete hydrochloric acid.

This is the normal appearance of the gastric fundal mucosa, with short pits lined by pale columnar mucus cells leading into long glands which contain bright pink parietal cells that secrete hydrochloric acid.

NEWS ARTICLE: new strains of cannabis NO THC, HIGH CBD. the new medical marijuana?

CANNABIS CULTURE - A company in Israel announced recently that it is the first to develop a strain of cannabis low in THC and high in cannabidiol (CBD) using the natural breeding process with no unnatural genetic modifications.

Another reminder, parietal cells are pink

Another reminder, parietal cells are pink

Pseudomembranous Colitis: The disease is treated either with oral vancomycin or with intravenous metronidazole.

Not every medical condition calls for antibiotics. Yet, on many occasions patients with non-bacterial related illnesses – such as the common.

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