Marie Curie was a woman before her time. Born in 1867, in Poland, she was a genius in physics and in chemistry; she is the first woman ever to receive a Nobel Prize and the only woman in history to receive two Nobel Prizes.
Isadora Duncan. Inventor of American modern dance. Shifted the focus of dance from the stifling emphasis on feet to the soulful, expressive, liberated solar plexus. Made dance more about freedom and emotions and introduced movement inspired by nature, athleticism, and folk dance, among other things. Muse to many artists across many genres.