How to Cook Salmon in the Oven. If you want "easy, fancy," it doesn't get much better than roasted salmon fillets in a pan. It can be one of your new favorite healthy weeknight date night dinners, an al fresco meal with friends, or dinner to impress your in-laws. Roast salmon will rise to the occasion. This is the easiest, simplest way to get food on the table fast. Make this recipe once and you'll always have ideas for dinner; you'll never wonder what to do with salmon again.