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The ultimate liver detox: Coffee enemas Tried my first one today. Noticed a difference right away. Even going for a second one. Be careful if you don't tolerate caffeine. Definitely use organic coffee but start with decaf if you can't tolerate caffeine and work your way up. I was able to hold it the full 20 on the first try. I ordered a bpa free plastic kit off amazon for $11 and organic enema coffee as well. Good luck!