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Peter Flohr
Peter Flohr • 2 years ago

Image: This transmission electron micrograph shows a Langerhans cell (purple) exiting an isolated epithelium to disseminate the HIV-1 infection. A long cytoplasmic extension of the Langerhans cell remains anchored between basal keratinocytes and contains a large vacuole with one HIV-1BaL virion (red) inside. Epithelial sheets were inoculated with the virus by centrifugation (i.e., spinoculation) for 2 hours and then fixed in Karnovsky's fixative for electron microscopy.

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