Sandro Boticelli's "The Birth of Venus", 1486, Galleria degli Uffizi, Florence. Most paintings of women during the middle Ages symbolize the Virgin Mary, showing her in a demure appearance with an angelic smile and covered head. So Botticelli's depiction of a beautiful goddess, not only an obvious symbol of pagan mythology but also painted as a nude was groundbreaking.
"Lady Flora, Goddess of Blossoms and Flowers", 1880, by Evelyn de Morgan (English, 1855-1919). This work derives from de Morgan's studies of Botticelli, particularly "Primavera" and "The Birth of Venus", at the Uffizi gallery in Florence. In Roman mythology, the nymph Chloris is transformed into the goddess Flora, the Mother of Flowers.