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Bupropion (Wellbutrin, Zyban) is an atypical antidepressant and smoking cessation aid. Its chemical name is β-keto-3-chloro-N-tert-butylamphetamine, a substituted cathinone (β-ketoamphetamine), as well as substituted amphetamine. Its primary action is thought to be NE-DA reuptake inhibition. It binds selectively to the dopamine transporter, but its behavioural effects have often been attributed to its inhibition of NE reuptake. It also acts as a nicotinic ACh receptor antagonist.
NMDA receptor antagonists are a class of anesthetics that work to antagonize, or inhibit the action of, the N-methyl d-aspartate receptor (NMDAR). They are used as anesthesia for animals and, less commonly, for humans; the state of anesthesia they induce is referred to as dissociative anesthesia. Memantine is an uncompetitive NMDA channel blocker. Memantine is the first in a novel class of Alzheimer's disease medications acting on the glutamatergic system by blocking NMDA glutamate receptors.
Naloxone is an opioid inverse agonist drug developed by Sankyo in the 1960s.Naloxone is a drug used to counter the effects of opiate overdose, for example heroin or morphine overdose. It is marketed under various trademarks including Narcan, Nalone, and Narcanti.
Bupropion (Wellbutrin, Zyban, Voxra, Budeprion, Prexaton, Elontril or Aplenzin ) is an atypical antidepressant and smoking cessation aid. It is a norepinephrine-dopamine reuptake inhibitor. It is also a nicotinic acetylcholine receptor antagonist. Treatment of Hypoactive Sexual Desire Disorder (HSDD) in women.
Dextrorphan (DXO) is a psychoactive drug of the morphinan chemical class which acts as an antitussive or cough suppressant and dissociative hallucinogen.Dextrorphan is an NMDA antagonist and contributes to the abuse liability of dextromethorphan.σ1 and σ2 sigma receptor agonist.α3β4, α4β2, and α7 nicotinic acetylcholine receptor antagonist.
Naproxen (brand names: Aleve, Naprosyn and many others) usually sold as the sodium salt naproxen sodium is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (which puts it in the same class as ibuprofen) and is commonly used for relief of a wide variety of pain, fever, swelling and stiffness. It is the preferred NSAID for long-term use in people with a high risk of cardiovascular complications, due to its relatively low risk of causing such complications.