Naloxone is an opioid inverse agonist drug developed by Sankyo in the 1960s.Naloxone is a drug used to counter the effects of opiate overdose, for example heroin or morphine overdose. It is marketed under various trademarks including Narcan, Nalone, and Narcanti.
2-Mercaptoethanol (also β-mercaptoethanol, BME, 2BME, 2-ME or β-met) is the chemical compound with the formula HOCH2CH2SH. ME or βME, as it is commonly abbreviated, is used to reduce disulfide bonds and can act as a biological antioxidant by scavenging hydroxyl radicals (amongst others). It is widely used because the hydroxyl group confers solubility in water and lowers the volatility. Due to its diminished vapor pressure, its odour, while unpleasant, is less objectionable than related thiols.
NPH insulin (or neutral protamine Hagedorn) (Humulin N, Novolin N, Novolin NPH, NPH Iletin II, & isophane insulin), is an intermediate-acting insulin. It is a suspension of crystalline zinc insulin combined with the positively charged polypeptide, protamine. When injected subcutaneously, it has an intermediate duration of action, meaning longer than that of regular insulin, and shorter than ultralente, glargine or detemir.
Dextrorphan (DXO) is a psychoactive drug of the morphinan chemical class which acts as an antitussive or cough suppressant and dissociative hallucinogen.Dextrorphan is an NMDA antagonist and contributes to the abuse liability of dextromethorphan.σ1 and σ2 sigma receptor agonist.α3β4, α4β2, and α7 nicotinic acetylcholine receptor antagonist.
Clofibrate (tradename Atromid-S) is an organic compound. It is marketed as a fibrate. It is a lipid-lowering agent used for controlling the high cholesterol and triacylglyceride level in the blood. It increases lipoprotein lipase activity to promote the conversion of VLDL to LDL, and hence reduce the level of VLDL. It can increase the level of HDL as well.
Sugammadex (Bridion) reverses neuromuscular blockade by rocuronium in general anaesthesia. It is the first selective relaxant binding agent (SRBA). The main advantage is reversal of neuromuscular blockade without relying on inhibition of acetylcholinesterase. It is therefore associated with much greater cardiovascular and autonomic stability. There has been little choice previously apart from the use of suxamethonium. www.ncbi.nlm.nih....