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  • Jessica Mandula

    Methoxetamine (MXE), or 3-MeO-2-Oxo-PCE is a dissociative anesthetic that has been sold as a designer drug.[1][2] Methoxetamine differs from many dissociatives such as ketamine and phencyclidine that were developed as pharmaceuticals in that it was designed for grey market distribution.[2][3] Pharmacologically, methoxetamine acts as a NMDA receptor antagonist. Unlike the related compound ketamine, MXE has appreciable affinity for the serotonin transporter.[4]

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Guaifenesin is thought to act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi.

NMDA receptor antagonists are a class of anesthetics that work to antagonize, or inhibit the action of, the N-methyl d-aspartate receptor (NMDAR). They are used as anesthesia for animals and, less commonly, for humans; the state of anesthesia they induce is referred to as dissociative anesthesia. Memantine is an uncompetitive NMDA channel blocker. Memantine is the first in a novel class of Alzheimer's disease medications acting on the glutamatergic system by blocking NMDA glutamate receptors.

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Methotrexate (rINN) [Trexall], abbreviated MTX and formerly known as amethopterin, is an antimetabolite and antifolate drug.

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Dihydrotachysterol (DHT) is a synthetic vitamin D analog activated in the liver that does not require renal hydroxylation like vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). DHT has a rapid onset of action (2 hours), a shorter half-life, and a greater effect on mineralization of bone salts than does vitamin D

Naproxen (brand names: Aleve, Naprosyn and many others) usually sold as the sodium salt naproxen sodium is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (which puts it in the same class as ibuprofen) and is commonly used for relief of a wide variety of pain, fever, swelling and stiffness. It is the preferred NSAID for long-term use in people with a high risk of cardiovascular complications, due to its relatively low risk of causing such complications.

Dextrorphan (DXO) is a psychoactive drug of the morphinan chemical class which acts as an antitussive or cough suppressant and dissociative hallucinogen.Dextrorphan is an NMDA antagonist and contributes to the abuse liability of dextromethorphan.σ1 and σ2 sigma receptor agonist.α3β4, α4β2, and α7 nicotinic acetylcholine receptor antagonist.

Phosgenite from Monteponi Mine, Iglesias, Carbonia-Iglesias Prov., Sardinia, Italy

Clofibrate (tradename Atromid-S) is an organic compound. It is marketed as a fibrate. It is a lipid-lowering agent used for controlling the high cholesterol and triacylglyceride level in the blood. It increases lipoprotein lipase activity to promote the conversion of VLDL to LDL, and hence reduce the level of VLDL. It can increase the level of HDL as well.