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    P values, the 'gold standard' of statistical validity, are not as reliable as many scientists assume. One researcher suggested rechristening the methodology “statistical hypothesis inference testing”, presumably for the acronym it would yield. Here we explain why if you think you can trust 'em, you should think again. www.nature.com/... Nature Publishing Group

    CRISPR, the disruptor : Nature News & Comment

    The quantum source of space-time : Nature News & Comment

    Today is #DNAday a holiday celebrated on April 25 which is the day in 1953 when James Watson and Francis Crick published papers in Nature on the structure of DNA. Credit: Nature Publishing Group

    It could have been revolutionary but just a few months after it was published in Nature, a new technique that would have allowed scientists to easily discern the atomic structure of molecules is on the ropes. Does a correction and a failure to reproduce the technique in other labs spell the end for 'crystal-free crystallography'? www.nature.com/...

    Science publishing: The trouble with retractions : Nature News

    Should we set limits on what science can probe? Are some areas too questionable to investigate? Nature explores taboo genetics - the genetics of IQ, race, sexuality and violence - and the scientists that have crossed the red line to work on them. A poll asks if you think each of these areas should be off-limits to scientists... www.nature.com/... Nature Publishing Group

    Wow! Gravitational lensing - the bending of light by stars - has been reproduced on a microchip. “This is indeed the first time an exact solution of Einstein's equations was mimicked” using an optical model, says physicist Ulf Leonhardt. The simplicity of the experiment “beautifully illustrates some of the ideas of general relativity”, he adds. www.nature.com/... Credit: Sheng, C.et al. Nature Publishing Group

    The cost of publishing: journal prices vary with influence and business model - and cheap open-access journals raise questions about the value publishers add for their money. #OA #open Nature Publishing Group Credit: Nature

    By looking at the the detailed structure of the radiation left over from the Big Bang, two cosmologists have shown that the Universe might be shaped like a saddle. If their model is correct, it would overturn the long-held belief that the cosmos is flat. www.nature.com/... CREDIT: ESA Nature Publishing Group

    Job satisfaction [among scientists]: Turbulent times : Naturejobs

    Women in Science: Despite improvements, female scientists continue to face discrimination, unequal pay and funding disparities. www.nature.com/... #women #science #sexism Nature Publishing Group

    ! Nature, Volume 497 Number 7449. A three-dimensional view of intact mouse hippocampus rendered transparent, showing neurons expressing eYFP (green), parvalbumin (red) and glial fibrillary acidic protein (blue). Cover: Kwanghun Chung & Karl Deisseroth, HHMI/Stanford Univ. Nature Publishing Group

    Leptons and Quarks (top) and three forces of nature (bottom): From “A Unified Theory of Elementary Particles and Forces” by Howard Georgi, in Scientific American, April 1981. Graphics by Gabor Kiss

    Nature, Volume 499 Number 7457. Phages naturally coexist in abundance with their bacterial hosts in the mammalian gut. Antibiotic treatment can negatively affect the gut environment and cause immune and metabolic deficiencies. (Cover illustration: Jenn Hinkle) Nature Publishing Group

    Nature, Volume 497 Number 7447. Genetically modified crops, we were promised, would deliver a second green revolution. In this special issue, Nature charts the development of GMO technology in the past three decades and looks for the green shoots that might form the basis of the next generation of GMOs. Cover: Kelly Krause/Nature (photo: Nagy-Bagoly Arpad/Shutterstock) Nature Publishing Group

    Happy Darwin Day! Here’s our free special from the archives on his life, science and legacy.

    Nature, Volume 510 Number 7503. Many of the high-resolution membrane protein structures published recently are notable for the presence of lipids closely associated with the protein, prompting the question, how are these lipids influencing membrane complex structure? On the cover, IM-MS captures a native membrane protein complex emerging from an ion mobility cell. Shown is the ammonia channel in apo, one- and two-lipid bound states. Cover: Arthur Laganowsky

    Lifespans predictable at early age Worm study suggests that activity in mitochondria determines ageing.

    First results from psychology’s largest reproducibility test Crowd-sourced effort raises nuanced questions about what counts as replication.

    "This is not a reform — this is a liquidation of science in Russia” In a move that has outraged researchers, the 290-year-old Russian Academy of Sciences is to be placed under the control of the Russian government, after the country’s lower house of parliament voted to approve a law that would change how the academy's 436 institutes and 45,000 staff are managed. www.nature.com/... Nature Publishing Group