Homemade Diaper Rash Ointment! ingredients: Desitin, A & D Ointment or Vaseline, Lotrimin or Nystatin which is a prescription anti fungal medication, and Maalox or Mylanta. Mix equal parts Desitin, anti fungal ingredient, and A & D ointment or Vaseline. Then add a cap full of the anti acid, Maalox or Mylanta. Mix it all together. You may have to adjust. If it’s too runny, use more Vaseline, or Desitin. Mix until it’s a thick paste and will stick. Apply it at every diaper change.