Put everything for one day (outfit, hair bow, pj) in a huge zip loc bag. Carry just that bag into the hotel instead of the massive suitcase. We did this for our 10 day trip in which we stayed in 9 different hotels. I used plastic grocery sacks labeled with city's name. Each bag had both kids outfits, pjs, and their pull ups.
How to make a simple Kids Travel Kit Binder that will keep them busy and happy with fun activities for long road trips. Includes an attached marker and holder, plus 150+ free printable kids travel activities!