Dogue de Bordeaux (French Mastiff) - history is debated. The only breed that most people agree was used is the Mastiff. Other than that, some people believe they're from the Tibetan Mastiff, others believe they're from Neapolitan Mastiffs.
The Spinone, also known as the Spinone Italiano, Spinone or Italian Griffon (Spinone is preferred as the breed is unique and indivisible) is an ancient breed dating back to as early as 500 B. ( Photo by Timberdoodle Kennels LLC )