Pray hardest when it’s hardest to pray? I don’t think this means we should pray hardest when we’re in the most trouble. Most of us find it pretty easy to pray when we need God to get us out of a tight spot. For me, this quote means that I need to pray hardest when I’m . . . . . . exhausted . . . excited . . . angry . . . anxious . . . annoyed . . . busy . . . behind . . . distracted.