Tactile journals combine creativity, early literacy, and the development of fine motor skills in an art activity for children who are blind or visually impaired, including those who have multiple disabilities or deafblindness.
Two Theories of Alzheimer's Diseasea a ..... The original amyloid hypothesis has been modified to implicate soluble oligomers (rather than plaques) as the neurotoxic trigger. b ..... The vascular hypothesis posits that amyloidogenesis is a consequence of hypoperfusion. ----- Some evidence suggests that the two insults may be synergistic, highlighting the need to better integrate both theories.