In the beginning of the play Margaret warns Buckingham of his imminent death. She says O Buckingham, take heed of yonder dog!/ Look when he fawns, he bites; and when he bites,/ His venom tooth will rankle to the death./ Have not to do with him. Beware of him./ Sin, death, and hell have set their marks on him,/ And all their ministers attend on him" (1.3.295-300). Buckingham does not heed this warning which foreshadows what is to come for Buckingham
Macduff, commits the same crime as Macbeth but it is seen as justice, because of Macbeths own crime. In Macbeth justice is seen as restoring order, Macduff makes emends with those of Scotland, and stays loyal by killing Macbeth.
Henry Stafford, Duke of Buckingham, KG September 1455 – 2 November played a major role in King Richard III's rise and He is also one of the primary suspects in the disappearance (and presumed murder) of the Princes in the Tower.