Construct the design piece by piece. Purposefully add images and typography. Each element should add significance to the overall design. Unneeded elements can muddle the design, confuse the readers and ultimately obscure the message.
The most important step to starting any design that has accompanying text is to read the text! You need to know what the message is. Otherwise, no matter how compelling the visual, if it doesn't sync with the words, the reader is lost.